Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 18/20 | 0.77 |
| ▸ | CA2 | P00918 | 18/20 | 0.77 |
| ▸ | CA9 | Q16790 | 13/20 | 0.77 |
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | CA7 | P43166 | 4/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.54 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584427 | 0.98 | CA1 (0.74) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11593138 | 0.87 | CA1 (1.00) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11745911 | 0.80 | CA1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4211542 | 0.78 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL495977 | 0.78 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL495979 | 0.78 | CA1 (0.46) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18063393 | 0.77 | CA1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL18086664 | 0.77 | CA1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1920255 | 0.77 | CA1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL5365363 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130115624-A1 | Methods To Identify Modulators | GIVAUDAN S.A. (CH) | 2013-05-09 | — | — | US | disclosed |
| EP-2567229-A1 | METHODS TO IDENTIFY MODULATORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| EP-2567231-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138456-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011138455-A1 | METHODS TO IDENTIFY MODULATORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |