Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.33 |
| ▸ | AOC2 | O75106 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162816 | 0.82 | — | — | |
| SCHEMBL11780411 | 0.82 | NPC1 (0.36) | NPC1 | |
| SCHEMBL20713619 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL2770966 | 0.79 | — | — | |
| SCHEMBL18824825 | 0.77 | — | — | |
| SCHEMBL1860292 | 0.77 | — | — | |
| SCHEMBL24272656 | 0.76 | NPC1 (0.30) | NPC1 | |
| SCHEMBL18239672 | 0.76 | SPHK1 (0.37) | SPHK1NPC1 | |
| SCHEMBL666787 | 0.76 | SPHK1 (0.37) | SPHK1NPC1 | |
| SCHEMBL578882 | 0.76 | SPHK1 (0.41) | SPHK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226186-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226186-A1 | RAS INHIBITORS | KRAS, NRAS, HRAS | SPHK1 3694/4885DCPS 3110/4885AOC2 4551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.