Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903645 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1LMNAIDO1GLA | |
| SCHEMBL14038382 | 0.73 | KDM4E (0.33) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL10139091 | 0.72 | KDM4E (0.32) | KDM4EALDH1A1LMNAGLAGAA | |
| SCHEMBL12090830 | 0.71 | — | — | |
| SCHEMBL2930119 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1LMNAIDO1GLA | |
| SCHEMBL25911070 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1LMNAIDO1GLA | |
| SCHEMBL7350230 | 0.70 | — | — | |
| SCHEMBL29625025 | 0.70 | — | — | |
| SCHEMBL2414672 | 0.70 | — | — | |
| SCHEMBL275143 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |