Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.73 |
| ▸ | HTR2A | P28223 | 11/20 | 0.73 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343699 | 1.00 | HTR2C (0.73) | HTR2CHTR2ANOTUMSIGMAR1HTR1A | |
| SCHEMBL6711152 | 0.84 | HTR2A (1.00) | HTR2CHTR2ANOTUMSIGMAR1 | |
| SCHEMBL29391845 | 0.84 | HTR2A (1.00) | HTR2CHTR2ANOTUMSIGMAR1 | |
| Hydrochloric Acid SCHEMBL6715337 | 0.83 | HTR2A (0.97) | HTR2CHTR2ANOTUMSIGMAR1 | |
| SCHEMBL18911623 | 0.81 | HTR2A (0.69) | HTR2CHTR2ANOTUMSIGMAR1HTR1A | |
| SCHEMBL18911621 | 0.75 | HTR2A (0.73) | HTR2CHTR2ANOTUMSIGMAR1HTR1A | |
| SCHEMBL30684257 | 0.73 | HTR2A (0.56) | HTR2CHTR2ANOTUMSIGMAR1HTR1A | |
| SCHEMBL10735669 | 0.73 | HTR2A (0.56) | HTR2CHTR2ANOTUMSIGMAR1HTR1A | |
| SCHEMBL30703022 | 0.72 | HTR2A (0.64) | HTR2CHTR2ANOTUMSIGMAR1HTR1A | |
| SCHEMBL761931 | 0.72 | HTR2A (0.64) | HTR2CHTR2ANOTUMSIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017088746-A1 | NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR AND APPLICATION THEREOF | 南京圣和药业股份有限公司 | 2017-06-01 | — | — | WO | disclosed |
| WO-2011139242-A2 | PROCESS FOR THE PREPARATION OF 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE DERIVATIVES | USTAV EXPIREMENTÁLNEJ FARMAKOLÓGIE A TOXIKOLÓGIE SAV (SK) | 2011-11-10 | — | — | WO | disclosed |