Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 15/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.46 |
| ▸ | FLT3 | P36888 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561327 | 0.84 | CCR1 (0.58) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL18397077 | 0.79 | PIM1 (0.52) | CSF1RFLT3KDRLRRK2ACVR1B | |
| SCHEMBL29538946 | 0.79 | PIM1 (0.52) | CSF1RFLT3KDRLRRK2ACVR1B | |
| SCHEMBL14447156 | 0.79 | FYN (0.58) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL24316789 | 0.77 | FYN (0.54) | CSF1RKDRLRRK2ACVR1BTGFBR1 | |
| SCHEMBL29539345 | 0.77 | FYN (0.54) | CSF1RKDRLRRK2ACVR1BTGFBR1 | |
| SCHEMBL29736768 | 0.77 | KDR (0.52) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL574068 | 0.77 | KDR (0.52) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL16029060 | 0.77 | CSF1R (0.51) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL11983571 | 0.77 | CCR1 (0.55) | KDRLRRK2ACVR1BTGFBR1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |