SCHEMBL25911682

SCHEMBL25911682

Clc1ccc(-c2cc3ccccc3c3ccccc23)c(-c2ccc3oc4ccccc4c3c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.49
TNKS O95271 2/20 0.39
KDM4E B2RXH2 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GPR84 Q9NQS5 1/20 0.37
IDO1 P14902 2/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
ADORA3 P0DMS8 2/20 0.35
BCAT1 P54687 1/20 0.35
THRB P10828 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25911712 0.92 AHR (0.56) AHRTNKSKDM4EKMT2AMEN1
SCHEMBL22810278 0.85 AHR (0.57) AHRTNKSKDM4EKMT2AMEN1
SCHEMBL22141151 0.84 KDM4E (0.49) AHRKDM4EKMT2AMEN1NPC1
SCHEMBL25912108 0.83 CYP1B1 (0.46) ALDH1A1MAPTHPGDGPR84
SCHEMBL21795115 0.82 AHR (0.47) AHRTNKSKDM4EKMT2AMEN1
SCHEMBL12069425 0.81 CYP11B1 (0.46) AHRKDM4EKMT2AMEN1NPC1
SCHEMBL15195401 0.81 MAPT (0.41) AHRKDM4EKMT2AMEN1NPC1
SCHEMBL22058746 0.80 AHR (0.57) AHRTNKSKDM4EKMT2AMEN1
SCHEMBL25911205 0.80 CYP2A6 (0.48) ALDH1A1HPGDGPR84
SCHEMBL12070716 0.80 CYP11B1 (0.45) KDM4EKMT2AMEN1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146343-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-08-03 WO disclosed