Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25912066 | 0.91 | TMPRSS2 (0.37) | TMPRSS2LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL24916843 | 0.90 | TMPRSS2 (0.37) | TMPRSS2LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL25925050 | 0.90 | TMPRSS2 (0.37) | TMPRSS2LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL25912389 | 0.90 | TMPRSS2 (0.38) | TMPRSS2LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL25912526 | 0.89 | TMPRSS2 (0.38) | TMPRSS2LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL25912578 | 0.88 | TMPRSS2 (0.37) | TMPRSS2LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL25912090 | 0.88 | TMPRSS2 (0.36) | TMPRSS2LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL25912097 | 0.88 | TMPRSS2 (0.35) | TMPRSS2LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL24789400 | 0.88 | TMPRSS2 (0.35) | TMPRSS2LMNASMN1; SMN2NPC1MAPT | |
| SCHEMBL23959928 | 0.87 | TMPRSS2 (0.61) | TMPRSS2LMNASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233593-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-07-27 | — | — | US | disclosed |
| US-11638715-B2 | Orally-bioavailable nucleoside analogs | VenatoRx Pharmaceuticals, Inc. (US) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11638715-B2 | Orally-bioavailable nucleoside analogs | SLC29A2, SLC29A1, PNP | TMPRSS2 100/4885LMNA 1629/4885SMN1; SMN2 862/4885 |
| US-20230233593-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | SLC29A2, SLC29A1, PNP | TMPRSS2 100/4885LMNA 1629/4885SMN1; SMN2 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.