Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.39 |
| ▸ | CSF1R | P07333 | 3/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 11/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910172 | 0.90 | BRAF (0.45) | P2RX3PDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25910551 | 0.85 | CSF1R (0.49) | P2RX3PDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25912706 | 0.83 | CSF1R (0.43) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25910279 | 0.83 | CSF1R (0.43) | P2RX3PDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25910797 | 0.82 | PDGFRB (0.39) | P2RX3PDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25912627 | 0.81 | PDGFRB (0.46) | P2RX3PDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25910567 | 0.81 | BRAF (0.42) | P2RX3PDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25909917 | 0.81 | PDGFRB (0.52) | P2RX3PDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25910170 | 0.81 | CSF1R (0.48) | P2RX3PDGFRBCSF1RPDGFRALCK | |
| SCHEMBL25910169 | 0.81 | CSF1R (0.48) | P2RX3PDGFRBCSF1RPDGFRALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |