⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17951155 | 0.81 | — | — | |
| SCHEMBL19965798 | 0.78 | PIM1 (0.33) | — | |
| SCHEMBL17951427 | 0.75 | — | — | |
| SCHEMBL22765714 | 0.74 | — | — | |
| SCHEMBL20934998 | 0.74 | — | — | |
| SCHEMBL23523675 | 0.72 | — | — | |
| SCHEMBL20935042 | 0.70 | MAP3K12 (0.31) | — | |
| SCHEMBL21919424 | 0.70 | — | — | |
| SCHEMBL24904058 | 0.70 | CHRM2 (0.32) | — | |
| SCHEMBL23342242 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |