SCHEMBL2591346

SCHEMBL2591346

CCCCCCCCCC[Si](C)(C)CC[C@@]1(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1N

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 3/20 0.33
▸ SPHK2 Q9NRA0 3/20 0.31
▸ SPHK1 Q9NYA1 3/20 0.31
▸ GBA1 P04062 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ ADORA2A P29274 2/20 0.31
▸ ADORA2B P29275 2/20 0.31
▸ GJB2 P29033 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7623220 0.86 SPHK2 (0.36) SPHK2SPHK1GBA1GAA
SCHEMBL29555015 0.80 GBA1 (0.36) OGAGBA1GAAMEN1KMT2A
SCHEMBL7628312 0.80 CETP (0.39) MEN1KMT2A
SCHEMBL5551957 0.75 GAA (0.37) GAA
SCHEMBL9699515 0.75 GAA (0.37) GAA
SCHEMBL25366499 0.75 GAA (0.37) GAA
SCHEMBL19326770 0.75 GAA (0.37) GAA
SCHEMBL22409570 0.75 GAA (0.37) GAA
SCHEMBL1401860 0.75 GAA (0.37) GAA
SCHEMBL9309804 0.75 GAA (0.37) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2563337-B1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2017-07-26 — — EP disclosed
EP-2563337-A1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE Salama, Zoser B. (DE) 2013-03-06 — — EP disclosed
WO-2011134675-A1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2011-11-03 — — WO disclosed
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