Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.93 |
| ▸ | DAO | P14920 | 1/20 | 0.93 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.93 |
| ▸ | CES2 | O00748 | 3/20 | 0.74 |
| ▸ | CES1 | P23141 | 3/20 | 0.74 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28946408 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11792463 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28630221 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11142371 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL10713850 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2981275 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL128630 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2551626 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11799336 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL29053364 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118914123-A | Method for measuring concentration of carbohydrazide in wet maintenance agent of steam generator of nuclear power station | 苏州热工研究院有限公司 | 2024-11-08 | — | — | CN | claimed |
| US-20240099961-A1 | FERMENTED EXTRACT OF LONGOZA SEEDS | L V M H RECHERCHE (FR) | 2024-03-28 | — | — | US | claimed |
| EP-4271208-A1 | FERMENTED EXTRACT OF LONGOZA SEEDS | L V M H RECHERCHE (FR) | 2023-11-08 | — | — | EP | claimed |
| WO-2022144513-A1 | FERMENTED EXTRACT OF LONGOZA SEEDS | L V M H RECHERCHE (FR) | 2022-07-07 | — | — | WO | claimed |
| CN-118914123-A | Method for measuring concentration of carbohydrazide in wet maintenance agent of steam generator of nuclear power station | 苏州热工研究院有限公司 | 2024-11-08 | — | — | CN | disclosed |
| US-20240099961-A1 | FERMENTED EXTRACT OF LONGOZA SEEDS | L V M H RECHERCHE (FR) | 2024-03-28 | — | — | US | disclosed |
| EP-4271208-A1 | FERMENTED EXTRACT OF LONGOZA SEEDS | L V M H RECHERCHE (FR) | 2023-11-08 | — | — | EP | disclosed |
| CN-116693772-A | Multifunctional agglomerated carboxylic acid water reducer and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-112899087-B | Kitchen oil stain cleaning agent | 华东师范大学 | 2022-07-08 | — | — | CN | disclosed |
| WO-2022144513-A1 | FERMENTED EXTRACT OF LONGOZA SEEDS | L V M H RECHERCHE (FR) | 2022-07-07 | — | — | WO | disclosed |
| CN-114600878-A | Emamectin benzoate and thiacloprid suspending agent and preparation method thereof | 山东汤普乐作物科学有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114213725-A | Flame-retardant sealing ring for motor of range hood | 宁国中奕橡塑有限公司 | 2022-03-22 | — | — | CN | disclosed |
| WO-2011139492-A2 | LOTION COMPOSITION FOR WET WIPES | THE PROCTER & GAMBLE COMPANY (US) | 2011-11-10 | — | — | WO | disclosed |
| US-7226579-B1 | Aerosol composition | DAIZO CO., LTD. (JP) | 2007-06-05 | — | — | US | disclosed |
| EP-1294979-A1 | FABRIC TREATMENT COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000994-A1 | FABRIC TREATMENT COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |
| US-6083854-A | COMPRISING WIPE SUBSTRATE HAVING EMULSION COMPRISING WATER, SILICONE BASE, POLYMER, STABILIZER PHENOXYETHANOL; USED FOR SKIN CARE, MAKE-UP REMOVAL; BABY CARE PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-07-04 | — | — | US | disclosed |
| US-6017869-A | Aqueous cleaning and disinfecting compositions which include quaternary ammonium compounds, block copolymer surfactants and further mitigating compounds which compositions feature reduced irritation | RECKITT & COLMAN INC. (US) | 2000-01-25 | — | — | US | disclosed |
| US-5695746-A | CONTAINING MENTHOL AND ANETHOLE | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| US-4401624-A | CARBOXYLIC ACIDS AND METAL SALTS | SYNTEX (U.S.A.) INC., 3401 HILLVIEW AVE., P.O. BPX 10850, PALO ALTO, CA. 94303, A CORP. OF DEL. | 1983-08-30 | — | — | US | disclosed |