⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914564 | 0.95 | — | — | |
| SCHEMBL24789463 | 0.92 | TMPRSS2 (0.31) | — | |
| SCHEMBL25914578 | 0.90 | TMPRSS2 (0.40) | — | |
| SCHEMBL24791771 | 0.90 | TMPRSS2 (0.40) | — | |
| SCHEMBL24917656 | 0.89 | TMPRSS2 (0.30) | — | |
| SCHEMBL24917345 | 0.88 | TMPRSS2 (0.35) | — | |
| SCHEMBL24916939 | 0.87 | TMPRSS2 (0.32) | — | |
| SCHEMBL25914328 | 0.86 | — | — | |
| SCHEMBL24789462 | 0.86 | — | — | |
| SCHEMBL25910251 | 0.86 | TMPRSS2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233593-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. | 2023-07-27 | — | — | US | disclosed |