Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13099750 | 0.85 | BCL2 (0.50) | BCL2PTGS2IDO1NISCHAGXT | |
| SCHEMBL24180478 | 0.85 | BCL2 (0.50) | BCL2PTGS2IDO1NISCHAGXT | |
| SCHEMBL19301066 | 0.84 | CYP17A1 (0.46) | BCL2PTGS2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL9287764 | 0.84 | BCL2 (0.49) | BCL2PTGS2IDO1NISCHAGXT | |
| SCHEMBL29489424 | 0.83 | BCL2 (0.62) | BCL2PTGS2IDO1NISCHAGXT | |
| SCHEMBL5547358 | 0.83 | BCL2 (0.62) | BCL2PTGS2IDO1NISCHAGXT | |
| SCHEMBL13197413 | 0.82 | AGXT (0.61) | BCL2PTGS2IDO1NISCHAGXT | |
| SCHEMBL12154152 | 0.82 | CYP17A1 (0.56) | BCL2CYP17A1CYP11B1CYP11B2NOTUM | |
| SCHEMBL16258028 | 0.82 | CYP17A1 (0.56) | BCL2CYP17A1CYP11B1CYP11B2NOTUM | |
| SCHEMBL16258055 | 0.82 | CYP17A1 (0.56) | BCL2CYP17A1CYP11B1CYP11B2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | AAAS, PROC, AADAC | BCL2 2274/4885PTGS2 887/4885IDO1 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.