Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23637709 | 0.81 | NR3C2 (0.57) | MAPK14MAPK13NR3C2 | |
| SCHEMBL29844360 | 0.77 | MAPK14 (0.67) | MAPK14MAPK13NR3C2 | |
| SCHEMBL23201782 | 0.77 | MAPK14 (0.67) | MAPK14MAPK13NR3C2 | |
| SCHEMBL25641487 | 0.76 | MAPK14 (0.68) | MAPK14MAPK13 | |
| SCHEMBL23201670 | 0.75 | MAPK14 (1.00) | MAPK14MAPK13 | |
| SCHEMBL29844532 | 0.75 | MAPK14 (1.00) | MAPK14MAPK13 | |
| SCHEMBL23015674 | 0.75 | NR3C2 (0.55) | MAPK14NR3C2 | |
| SCHEMBL29844362 | 0.75 | MAPK14 (1.00) | MAPK14MAPK13 | |
| SCHEMBL29844394 | 0.75 | MAPK14 (1.00) | MAPK14MAPK13 | |
| SCHEMBL23201717 | 0.75 | MAPK14 (1.00) | MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219489-A2 | MITOGEN-ACTIVATED PROTEIN KINASE INHIBITORS, METHODS OF MAKING, AND METHODS OF USE THEREOF | Washington University (US) | 2023-08-02 | — | — | EP | disclosed |