SCHEMBL25918324

SCHEMBL25918324

C=C(NCCCCn1c(CCCC)nc2c(N)nc3ccccc3c21)C1CCC(CN2C(=O)CC(SCC(=O)O)C2=O)CC1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.48
TLR8 Q9NR97 7/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23813751 1.00 TLR7 (0.48) TLR7TLR8
SCHEMBL22181062 0.94 TLR7 (0.49) TLR7TLR8
SCHEMBL20801449 0.94 TLR7 (0.49) TLR7TLR8
SCHEMBL22181004 0.94 TLR7 (0.49) TLR7TLR8
SCHEMBL20801362 0.88 TLR7 (0.49) TLR7TLR8
SCHEMBL24863776 0.86 TLR7 (0.46) TLR7TLR8
SCHEMBL23813750 0.84 TLR7 (0.47) TLR7TLR8
SCHEMBL22181005 0.84 TLR7 (0.47) TLR7TLR8
SCHEMBL20801632 0.84 TLR7 (0.47) TLR7TLR8
SCHEMBL24860124 0.83 TLR7 (0.53) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4218824-A2 IMMUNOCONJUGATE SYNTHESIS METHOD Bolt Biotherapeutics, Inc. (US) 2023-08-02 EP disclosed