Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21990677 | 0.87 | GRM2 (0.32) | GRM2 | |
| SCHEMBL25918343 | 0.85 | DPP4 (0.31) | GRM2 | |
| SCHEMBL21990688 | 0.77 | DPP4 (0.40) | GRM2 | |
| SCHEMBL21990566 | 0.77 | GRM2 (0.35) | GRM2 | |
| SCHEMBL30543379 | 0.72 | CLK4 (0.37) | GRM2 | |
| SCHEMBL1579192 | 0.72 | CLK4 (0.37) | GRM2 | |
| SCHEMBL21990516 | 0.71 | KDR (0.33) | — | |
| SCHEMBL21990520 | 0.70 | PIK3CD (0.34) | — | |
| SCHEMBL29261238 | 0.69 | CDK5 (0.35) | GRM2 | |
| SCHEMBL21990466 | 0.69 | PARP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880676-B1 | 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDIN-1-ONE DERIVATIVES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER | PFIZER (US) | 2023-08-02 | — | — | EP | disclosed |