Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317087 | 0.82 | PTK2 (0.36) | KMT2AALDH1A1KDM4EGAAPTGS2 | |
| SCHEMBL25317922 | 0.74 | CYP4F2 (0.35) | ALDH1A1GAAPTGS2BACE1SMN1; SMN2 | |
| SCHEMBL25316966 | 0.72 | CYP4F2 (0.32) | — | |
| SCHEMBL486163 | 0.70 | CCR1 (0.46) | SLC40A1KMT2ARAB9AHSP90AA1CXCR5 | |
| SCHEMBL24150563 | 0.69 | CCR1 (0.41) | SLC40A1KMT2ARAB9AHSP90AA1CXCR5 | |
| SCHEMBL51542 | 0.69 | CA1 (0.61) | SLC40A1KMT2ARAB9AHSP90AA1CXCR5 | |
| SCHEMBL1038893 | 0.69 | CCR1 (0.44) | SLC40A1KMT2ARAB9AHSP90AA1CXCR5 | |
| SCHEMBL2633881 | 0.69 | CCR1 (0.50) | SLC40A1KMT2ARAB9AHSP90AA1CXCR5 | |
| SCHEMBL29733038 | 0.69 | CCR1 (0.50) | SLC40A1KMT2ARAB9AHSP90AA1CXCR5 | |
| SCHEMBL17828095 | 0.68 | CCR1 (0.40) | KMT2ARAB9ACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |