Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.61 |
| ▸ | PARP2 | Q9UGN5 | 8/20 | 0.61 |
| ▸ | PARP6 | Q2NL67 | 7/20 | 0.61 |
| ▸ | PARP3 | Q9Y6F1 | 7/20 | 0.61 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27123231 | 0.90 | PARP1 (0.74) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL25890053 | 0.90 | PARP1 (0.59) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL25117743 | 0.88 | PARP1 (0.68) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL25919272 | 0.88 | PARP1 (0.64) | PARP1PARP2PARP6PARP3 | |
| SCHEMBL25117744 | 0.86 | PARP1 (0.83) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL30331823 | 0.86 | PARP1 (0.83) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL30331768 | 0.84 | PARP1 (0.74) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL25889585 | 0.83 | PARP1 (0.58) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26449464 | 0.83 | PARP1 (0.74) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL25889721 | 0.82 | PARP1 (0.73) | PARP1PARP2PARP6PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234952-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234952-A1 | PARP1 INHIBITORS AND USES THEREOF | PARP1, PARP11, PARP12 | PARP1 1/4885PARP2 5/4885PARP6 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.