Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | WNT3 | P56703 | 1/20 | 0.33 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321719 | 1.00 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDELANE | |
| SCHEMBL25321715 | 1.00 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDELANE | |
| SCHEMBL17113459 | 0.91 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDELANE | |
| SCHEMBL31133635 | 0.91 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDELANE | |
| SCHEMBL17113461 | 0.91 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDELANE | |
| SCHEMBL25650059 | 0.91 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDELANE | |
| SCHEMBL24366649 | 0.80 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDELANE | |
| SCHEMBL15017885 | 0.80 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDELANE | |
| SCHEMBL25322015 | 0.79 | — | — | |
| SCHEMBL11917918 | 0.78 | CHRM2 (0.42) | CHRM2CHRM1CHRM3HPGDELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |