Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25920173 | 0.83 | AXL (0.42) | HSD17B10HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL30579401 | 0.70 | SMPD3 (0.47) | HSD17B10HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL22792265 | 0.67 | SMPD3 (0.50) | HSD17B10HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL805457 | 0.65 | SMPD3 (0.55) | HSD17B10HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL30579408 | 0.63 | SMPD3 (0.55) | HSD17B10HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL29518379 | 0.62 | SMPD3 (0.51) | HSD17B10HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL17321392 | 0.62 | HTT (0.51) | HSD17B10HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL18717545 | 0.62 | PDE2A (0.61) | HSD17B10HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL30579467 | 0.61 | SMPD3 (0.53) | HSD17B10HPGDALDH1A1LMNAKDM4E | |
| SCHEMBL10042194 | 0.60 | HTT (0.58) | HSD17B10HPGDALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219501-A1 | COMPOUND CONTAINING 2,4-THIAZOLE RING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shandong University (CN) | 2023-08-02 | — | — | EP | disclosed |