Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 15/20 | 0.84 |
| ▸ | RAF1 | P04049 | 6/20 | 0.84 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | SRC | P12931 | 2/20 | 0.64 |
| ▸ | EGFR | P00533 | 4/20 | 0.63 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2975196 | 0.96 | MAP2K1 (0.84) | MAP2K1RAF1MAPK3MAPK1SRC | |
| SCHEMBL4954921 | 0.94 | MAP2K1 (0.73) | MAP2K1RAF1MAPK3MAPK1SRC | |
| SCHEMBL25920307 | 0.93 | MAP2K1 (0.72) | MAP2K1RAF1MAPK3MAPK1SRC | |
| SCHEMBL25920402 | 0.92 | MAP2K1 (0.70) | MAP2K1RAF1MAPK3MAPK1SRC | |
| SCHEMBL6382750 | 0.92 | MAP2K1 (1.00) | MAP2K1RAF1MAPK3MAPK1SRC | |
| SCHEMBL14116955 | 0.91 | MAP2K1 (0.72) | MAP2K1RAF1MAPK3MAPK1SRC | |
| SCHEMBL13915772 | 0.89 | MAP2K1 (0.69) | MAP2K1RAF1MAPK3MAPK1SRC | |
| SCHEMBL25920241 | 0.89 | SRC (0.66) | MAP2K1RAF1MAPK3MAPK1SRC | |
| SCHEMBL14116956 | 0.89 | EGFR (0.69) | MAP2K1RAF1MAPK3MAPK1SRC | |
| SCHEMBL13915779 | 0.88 | EGFR (0.68) | MAP2K1RAF1MAPK3MAPK1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141635-A2 | HER3 LIGANDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-27 | — | — | WO | disclosed |