Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033608 | 0.85 | BRD4 (0.54) | KMT2AMEN1SMN1; SMN2POLBTSHR | |
| SCHEMBL30498923 | 0.81 | BRD4 (0.59) | ALDH1A1HPGDLMNAPDE5AKMT2A | |
| SCHEMBL29033616 | 0.81 | BRD4 (0.59) | ALDH1A1HPGDLMNAPDE5AKMT2A | |
| SCHEMBL4986822 | 0.80 | KMT2A (0.50) | KDM4EALDH1A1HPGDLMNAPDE5A | |
| SCHEMBL4980044 | 0.80 | PDE5A (0.45) | KDM4EALDH1A1HPGDPDE5ACYP19A1 | |
| SCHEMBL4981854 | 0.78 | PDE5A (0.51) | KDM4EALDH1A1HPGDPDE5ACYP19A1 | |
| SCHEMBL8198142 | 0.78 | MEN1 (0.56) | KDM4EALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL4987382 | 0.76 | PDE5A (0.42) | KDM4EALDH1A1HPGDLMNAPDE5A | |
| SCHEMBL4983757 | 0.73 | PDE1B (0.45) | KDM4EALDH1A1HPGDLMNAPDE5A | |
| SCHEMBL4986240 | 0.73 | PDE5A (0.40) | KDM4EALDH1A1HPGDLMNAPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141114-A2 | SYNTHESIS OF BORON-CONTAINING AMIDOXIME REAGENTS AND THEIR APPLICATION TO SYNTHESIZE FUNCTIONALIZED OXADIAZOLE AND QUINAZOLINONE DERIVATIVES | LONG ISLAND UNIVERSITY (US) | 2023-07-27 | — | — | WO | disclosed |