Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25921506 | 1.00 | KDM4E (0.35) | KDM4EALDH1A1ALOX15CCRL2POLB | |
| SCHEMBL25921507 | 1.00 | KDM4E (0.35) | KDM4EALDH1A1ALOX15CCRL2POLB | |
| SCHEMBL25027119 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1ALOX15POLB | |
| SCHEMBL20832685 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL22227990 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL22227930 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL22227931 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28442281 | 0.77 | — | — | |
| SCHEMBL25820276 | 0.77 | KDM1A (0.42) | ALDH1A1ALOX15 | |
| SCHEMBL25921650 | 0.75 | KDM4E (0.35) | KDM4EALDH1A1ALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142754-A1 | EZH1/2 INHIBITOR, PREPARATION THEREOF, AND USE THEREOF IN ANTI-TUMOR THERAPY | 江苏天士力帝益药业有限公司 | 2023-08-03 | — | — | WO | disclosed |