Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25921602 | 1.00 | IRAK4 (0.37) | IRAK4ADRA1AKDM4EALDH1A1ALOX15 | |
| SCHEMBL25922269 | 1.00 | IRAK4 (0.37) | IRAK4ADRA1AKDM4EALDH1A1ALOX15 | |
| SCHEMBL25921595 | 1.00 | IRAK4 (0.37) | IRAK4ADRA1AKDM4EALDH1A1ALOX15 | |
| SCHEMBL16313526 | 1.00 | IRAK4 (0.37) | IRAK4ADRA1AKDM4EALDH1A1ALOX15 | |
| SCHEMBL24718088 | 0.85 | KDM4E (0.33) | IRAK4KDM4EALDH1A1ALOX15KMT2A | |
| SCHEMBL25921408 | 0.85 | KDM4E (0.33) | IRAK4KDM4EALDH1A1ALOX15KMT2A | |
| SCHEMBL25921366 | 0.85 | KDM4E (0.33) | IRAK4KDM4EALDH1A1ALOX15KMT2A | |
| SCHEMBL6125783 | 0.82 | IRAK4 (0.36) | IRAK4HRH3MELK | |
| SCHEMBL529404 | 0.82 | IRAK4 (0.36) | IRAK4HRH3MELK | |
| SCHEMBL17660501 | 0.82 | HRH3 (0.40) | IRAK4HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142754-A1 | EZH1/2 INHIBITOR, PREPARATION THEREOF, AND USE THEREOF IN ANTI-TUMOR THERAPY | 江苏天士力帝益药业有限公司 | 2023-08-03 | — | — | WO | disclosed |