SCHEMBL25924624

SCHEMBL25924624

CC1(C)c2ccccc2-c2c1c(-c1ccc(-c3ccc(-c4nc(-c5ccccc5)c5ccccc5n4)cc3)cc1)nc1c2oc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.41
MEN1 O00255 5/20 0.41
ATM Q13315 1/20 0.41
TSHR P16473 5/20 0.38
MAPT P10636 10/20 0.37
ALDH1A1 P00352 8/20 0.37
LMNA P02545 5/20 0.37
POLB P06746 3/20 0.37
HSD17B10 Q99714 3/20 0.37
USP2 O75604 1/20 0.37
HTT P42858 1/20 0.37
KDM4E B2RXH2 4/20 0.36
HPGD P15428 3/20 0.36
ADORA2A P29274 1/20 0.36
NPSR1 Q6W5P4 3/20 0.36
GAA P10253 2/20 0.36
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25924623 0.93 TSHR (0.41) KMT2AMEN1TSHRMAPTALDH1A1
SCHEMBL25925063 0.93 KMT2A (0.41) KMT2AMEN1ATMTSHRMAPT
SCHEMBL25924613 0.92 TSHR (0.42) KMT2AMEN1TSHRMAPTALDH1A1
SCHEMBL25924614 0.89 TSHR (0.39) KMT2AMEN1TSHRMAPTALDH1A1
SCHEMBL25924136 0.86 MEN1 (0.42) KMT2AMEN1ATMALDH1A1KDM4E
SCHEMBL25925061 0.85 TSHR (0.41) KMT2AMEN1TSHRMAPTALDH1A1
SCHEMBL25924616 0.84 TSHR (0.39) KMT2AMEN1TSHRMAPTALDH1A1
SCHEMBL25925054 0.84 TSHR (0.42) KMT2AMEN1TSHRMAPTALDH1A1
SCHEMBL25925062 0.82 TSHR (0.39) KMT2AMEN1TSHRMAPTALDH1A1
SCHEMBL25924620 0.80 MEN1 (0.33) KMT2AMEN1TSHRMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023138254-A1 HETEROCYCLIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL AND ELEMENT 上海八亿时空先进材料有限公司 2023-07-27 WO disclosed