Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ACP3 | P15309 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660520 | 0.81 | CA1 (0.58) | CA1CA2ACHEACP3ACACB | |
| SCHEMBL12870269 | 0.78 | CA1 (0.55) | CA1CA2ACHEACP3ACACB | |
| SCHEMBL13741075 | 0.78 | CA1 (0.55) | CA1CA2ACHEACP3ACACB | |
| SCHEMBL278257 | 0.78 | CA1 (0.55) | CA1CA2ACHEACP3ACACB | |
| SCHEMBL24105692 | 0.75 | CA1 (0.56) | CA1CA2ACHEACP3ACACB | |
| SCHEMBL8239398 | 0.75 | CA1 (0.56) | CA1CA2ACHEACP3ACACB | |
| SCHEMBL13462356 | 0.75 | CA1 (0.56) | CA1CA2ACHEACP3ACACB | |
| SCHEMBL327954 | 0.75 | CA1 (0.56) | CA1CA2ACHEACP3ACACB | |
| SCHEMBL11846483 | 0.75 | ACP3 (0.47) | ACP3ALDH1A1MEN1KMT2ADRD3 | |
| SCHEMBL19286211 | 0.75 | CA1 (0.56) | CA1CA2ACHEACP3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219502-A1 | IMIDAZO[1,5-A]PYRAZINE DERIVATIVES AS PI3KDELTA INHIBITORS | BeiGene, Ltd. (KY) | 2023-08-02 | — | — | EP | disclosed |