Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21939532 | 1.00 | KMT2A (0.49) | KMT2AHPGDHTTSMN1; SMN2USP2 | |
| SCHEMBL14394890 | 0.95 | SMN1; SMN2 (0.53) | KMT2AHPGDHTTSMN1; SMN2USP2 | |
| SCHEMBL9383 | 0.81 | USP2 (0.63) | KMT2AHPGDHTTSMN1; SMN2USP2 | |
| SCHEMBL14394851 | 0.78 | SMN1; SMN2 (0.54) | KMT2AHPGDHTTSMN1; SMN2USP2 | |
| SCHEMBL15492723 | 0.76 | SMN1; SMN2 (0.57) | KMT2AHPGDHTTSMN1; SMN2USP2 | |
| SCHEMBL26789172 | 0.75 | USP2 (0.70) | KMT2AHPGDHTTSMN1; SMN2USP2 | |
| SCHEMBL3154658 | 0.75 | USP2 (0.70) | KMT2AHPGDHTTSMN1; SMN2USP2 | |
| SCHEMBL26789169 | 0.75 | USP2 (0.70) | KMT2AHPGDHTTSMN1; SMN2USP2 | |
| SCHEMBL11060437 | 0.73 | HPGD (0.45) | KMT2AHPGDHTTSMN1; SMN2USP2 | |
| SCHEMBL18226082 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219502-A1 | IMIDAZO[1,5-A]PYRAZINE DERIVATIVES AS PI3KDELTA INHIBITORS | BeiGene, Ltd. (KY) | 2023-08-02 | — | — | EP | disclosed |