SCHEMBL25925817

SCHEMBL25925817

Cc1nsc(/N=N/c2ccc(O)c(/N=N/c3ccncc3)c2O)c1C#N

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.32
MEN1 O00255 5/20 0.32
MAPT P10636 5/20 0.32
ALDH1A1 P00352 3/20 0.32
HTT P42858 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
LMNA P02545 2/20 0.32
KCNH2 Q12809 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.32
AGTR1 P30556 1/20 0.31
HKDC1 Q2TB90 1/20 0.31
NPC1 O15118 1/20 0.31
IDE P14735 1/20 0.31
RAB9A P51151 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25925807 0.82
SCHEMBL25926940 0.82
SCHEMBL25925798 0.80
SCHEMBL25926010 0.78
SCHEMBL15049291 0.74 PIM1 (0.40) KMT2AMEN1MAPTALDH1A1HTT
SCHEMBL15049290 0.74 PIM1 (0.40) KMT2AMEN1MAPTALDH1A1HTT
SCHEMBL25925818 0.73 MEN1 (0.42) KMT2AMEN1MAPTALDH1A1HTT
SCHEMBL25925826 0.72 MEN1 (0.32) KMT2AMEN1MAPTALDH1A1HTT
SCHEMBL13708835 0.72 PLCG1 (0.44) KMT2AMEN1MAPTALDH1A1HTT
SCHEMBL25926006 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE AR, MAPT, NR5A1 KMT2A 1814/4885MEN1 67/4885MAPT 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.