⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282121 | 0.58 | — | — | |
| SCHEMBL4591206 | 0.56 | — | — | |
| SCHEMBL10670191 | 0.49 | — | — | |
| SCHEMBL460530 | 0.38 | — | — | |
| SCHEMBL9886121 | 0.38 | — | — | |
| SCHEMBL13113895 | 0.38 | — | — | |
| SCHEMBL6365769 | 0.38 | — | — | |
| SCHEMBL56545 | 0.37 | — | — | |
| Cyclohexane SCHEMBL6936788 | 0.37 | — | — | |
| SCHEMBL31154659 | 0.37 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595989-A1 | HETEROCYCLIC CHROMENE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2013-05-29 | — | — | EP | disclosed |
| WO-2011140425-A1 | HETEROCYCLIC CHROMENE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-11-10 | — | — | WO | disclosed |
| CN-1742015-A | Oxazolidinone and / or isoxazoline derivatives as antibacterial agents | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | CN | disclosed |
| CN-1742009-A | Oxazolidinones as antibacterial agents | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | CN | disclosed |
| CN-1653064-A | Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them | ASTRAZENECA AB (SE) | 2005-08-10 | — | — | CN | disclosed |
| CN-1649866-A | 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents | ASTRAZENECA AB (SE) | 2005-08-03 | — | — | CN | disclosed |
| CN-1165534-C | Heterocyclyl amino methyloxazolidinones as antibacterials | — | 2004-09-08 | — | — | CN | disclosed |
| CN-1437603-A | Oxazolidinone derivatives with antibiotic activity | ASTRAZENECA AB (SE) | 2003-08-20 | — | — | CN | disclosed |
| CN-1322203-A | Heterocyclic aminomethyl oxazolidinones as antibacterial agents | ASTRA ZENECA N V (SE) | 2001-11-14 | — | — | CN | disclosed |
| CN-1311787-A | oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | ASTRA ZENECA CO LTD (SE) | 2001-09-05 | — | — | CN | disclosed |
| CN-1304410-A | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | ASTRA ZENECA LTD (SE) | 2001-07-18 | — | — | CN | disclosed |