Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.59 |
| ▸ | KDM6B | O15054 | 1/20 | 0.59 |
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.58 |
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.58 |
| ▸ | VEGFA | P15692 | 3/20 | 0.55 |
| ▸ | FLT1 | P17948 | 3/20 | 0.55 |
| ▸ | TET3 | O43151 | 1/20 | 0.55 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.55 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.55 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.55 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.55 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25930804 | 0.88 | EGLN1 (0.75) | FTOEGLN1EGLN3VEGFAFLT1 | |
| SCHEMBL31203957 | 0.88 | EGLN1 (0.75) | FTOEGLN1EGLN3VEGFAFLT1 | |
| SCHEMBL25930317 | 0.87 | EGLN1 (0.70) | FTOEGLN1EGLN3VEGFAFLT1 | |
| SCHEMBL31204213 | 0.87 | EGLN1 (0.70) | FTOEGLN1EGLN3VEGFAFLT1 | |
| SCHEMBL31204216 | 0.86 | EGLN1 (0.60) | FTOEGLN1EGLN3VEGFAFLT1 | |
| SCHEMBL31204167 | 0.86 | EGLN1 (0.60) | FTOEGLN1EGLN3VEGFAFLT1 | |
| SCHEMBL25930882 | 0.86 | EGLN1 (0.60) | FTOEGLN1EGLN3VEGFAFLT1 | |
| SCHEMBL31204136 | 0.86 | EGLN1 (0.60) | FTOEGLN1EGLN3VEGFAFLT1 | |
| SCHEMBL25930999 | 0.86 | EGLN1 (0.60) | FTOEGLN1EGLN3VEGFAFLT1 | |
| SCHEMBL25930794 | 0.86 | EGLN1 (0.60) | FTOEGLN1EGLN3VEGFAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142214-A1 | 3-HYDROXY-5-(ISOXAZOL-5-YL) PYRIDINE FORMYLGLYCINE COMPOUNDS, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 中国药科大学 | 2023-08-03 | — | — | WO | disclosed |