Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5010643 | 0.84 | SMN1; SMN2 (0.55) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL16603216 | 0.83 | AR (0.59) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL25932840 | 0.83 | PIK3CD (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL21157991 | 0.82 | AR (0.58) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL15349087 | 0.80 | AR (0.56) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL28003521 | 0.80 | AR (0.56) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL4850658 | 0.79 | PIK3CD (0.61) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL16594438 | 0.77 | AR (0.56) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL16603218 | 0.76 | AR (0.56) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL31082099 | 0.76 | PIK3CD (0.58) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242535-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | BRISTOL MYERS SQUIBB CO (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242535-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | F2RL3, F2R, TMPRSS4 | AR 1550/4885PIK3CD 2401/4885PIK3CA 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.