Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.59 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.54 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.49 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493382 | 1.00 | CRBN (0.59) | CRBNCSNK1A1IKZF2IKZF1MAP1LC3B | |
| SCHEMBL26091706 | 1.00 | CRBN (0.59) | CRBNCSNK1A1IKZF2IKZF1MAP1LC3B | |
| SCHEMBL31668301 | 1.00 | CRBN (0.59) | CRBNCSNK1A1IKZF2IKZF1MAP1LC3B | |
| Hydrochloric Acid SCHEMBL30906201 | 0.99 | CRBN (0.58) | CRBNCSNK1A1IKZF2IKZF1MAP1LC3B | |
| SCHEMBL31034225 | 0.92 | CRBN (0.59) | CRBNCSNK1A1IKZF2IKZF1MAP1LC3B | |
| SCHEMBL26093667 | 0.92 | CRBN (0.59) | CRBNCSNK1A1IKZF2IKZF1MAP1LC3B | |
| SCHEMBL23350279 | 0.84 | CRBN (0.61) | CRBNIKZF1 | |
| SCHEMBL20046330 | 0.84 | CRBN (0.61) | CRBNIKZF1 | |
| SCHEMBL31033571 | 0.84 | CRBN (0.61) | CRBNIKZF1 | |
| SCHEMBL30351657 | 0.84 | CRBN (0.56) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |