Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 8/20 | 0.51 |
| ▸ | SRC | P12931 | 5/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | HCK | P08631 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | BTK | Q06187 | 7/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25933669 | 0.93 | EGFR (0.54) | KDRRETEGFRSRCPIK3CD | |
| SCHEMBL25933742 | 0.87 | BTK (0.59) | KDRRETEGFRSRCABL1 | |
| SCHEMBL25933728 | 0.87 | BTK (0.59) | KDRRETEGFRSRCABL1 | |
| SCHEMBL25472498 | 0.84 | BTK (0.62) | KDREGFRSRCBTKLCK | |
| SCHEMBL25933975 | 0.83 | EGFR (0.49) | KDRRETEGFRSRCPIK3CD | |
| SCHEMBL24197093 | 0.83 | BTK (0.60) | KDRRETEGFRSRCABL1 | |
| SCHEMBL25933740 | 0.82 | BTK (0.60) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL25933738 | 0.82 | BTK (0.63) | KDREGFRSRCPIK3CDABL1 | |
| SCHEMBL25933966 | 0.82 | EGFR (0.49) | KDRRETEGFRSRCPIK3CD | |
| SCHEMBL25933673 | 0.82 | BTK (0.49) | KDRRETEGFRSRCPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248833-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248833-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | BTK, WEE1, WEE2 | KDR 1977/4885RET 1868/4885EGFR 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.