Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.46 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 7/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.46 |
| ▸ | TEK | Q02763 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | CSK | P41240 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 4/20 | 0.44 |
| ▸ | YES1 | P07947 | 2/20 | 0.44 |
| ▸ | FGR | P09769 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | FRK | P42685 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | HCK | P08631 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25933965 | 0.92 | LCK (0.48) | SRCIGF1RBTKNUDT14NUDT5 | |
| SCHEMBL24196933 | 0.88 | BTK (0.61) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL25933975 | 0.84 | EGFR (0.49) | SRCBTKLCKKDRTEK | |
| SCHEMBL25933956 | 0.83 | EGFR (0.45) | SRCBTKLCKKDRTEK | |
| SCHEMBL25933954 | 0.82 | EGFR (0.42) | SRCIGF1RBTKLCKKDR | |
| SCHEMBL25933966 | 0.81 | EGFR (0.49) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL25933969 | 0.81 | BTK (0.56) | SRCIGF1RBTKNUDT14NUDT5 | |
| SCHEMBL30416459 | 0.80 | BTK (0.61) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL30415844 | 0.80 | BTK (0.63) | SRCBTKNUDT14NUDT5LCK | |
| SCHEMBL24192691 | 0.80 | BTK (0.63) | SRCBTKNUDT14NUDT5LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248833-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248833-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | BTK, WEE1, WEE2 | SRC 142/4885IGF1R 2006/4885BTK 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.