SCHEMBL25934617 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	USP30	Q70CQ3	1/20	0.44

▸	ESR2	Q92731	1/20	0.42

▸	DDB1	Q16531	1/20	0.38

▸	CRBN	Q96SW2	1/20	0.38

▸	NPC1	O15118	1/20	0.37

▸	RAB9A	P51151	1/20	0.37

▸	NR1H2	P55055	1/20	0.37

▸	ROCK1	Q13464	1/20	0.37

▸	BACE1	P56817	1/20	0.35

▸	BACE2	Q9Y5Z0	1/20	0.35

▸	HRH3	Q9Y5N1	1/20	0.35

▸	GPR119	Q8TDV5	8/20	0.35

▸	PRMT5	O14744	3/20	0.34

▸	WDR77	Q9BQA1	3/20	0.34

▸	NAMPT	P43490	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25934616	0.83	ESR2 (0.47)	USP30ESR2DDB1CRBNNPC1
SCHEMBL30014804	0.83	ESR2 (0.47)	USP30ESR2DDB1CRBNNPC1
SCHEMBL29676899	0.81	ESR2 (0.62)	USP30ESR2DDB1CRBNNPC1
SCHEMBL587184	0.81	ESR2 (0.62)	USP30ESR2DDB1CRBNNPC1
SCHEMBL27241645	0.79	USP30 (0.41)	USP30HRH3GPR119
SCHEMBL2118099	0.79	ESR2 (0.52)	USP30ESR2DDB1CRBNNPC1
SCHEMBL2515678	0.78	NR1H2 (0.61)	USP30ESR2DDB1CRBNNPC1
SCHEMBL29964782	0.78	NR1H2 (0.61)	USP30ESR2DDB1CRBNNPC1
SCHEMBL2589826	0.77	ROCK1 (0.48)	USP30ESR2DDB1CRBNNR1H2
SCHEMBL27459527	0.77	USP30 (0.48)	USP30DDB1CRBNNR1H2BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023109892-A1	COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF	海思科医药集团股份有限公司	2023-06-22	—	—	WO	disclosed