Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.50 |
| ▸ | WIZ | O95785 | 1/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31131367 | 1.00 | CRBN (0.57) | CRBNESR1IKZF2WIZIKZF1 | |
| Hydrochloric Acid SCHEMBL25430545 | 0.99 | CRBN (0.56) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL25934631 | 0.99 | CRBN (0.58) | CRBNESR1IKZF2WIZIKZF1 | |
| Hydrochloric Acid SCHEMBL25428073 | 0.98 | CRBN (0.57) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL25935537 | 0.96 | CRBN (0.59) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL20231971 | 0.93 | CRBN (0.61) | CRBNESR1IKZF2WIZIKZF1 | |
| Hydrochloric Acid SCHEMBL25427604 | 0.92 | CRBN (0.60) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL26198581 | 0.91 | CRBN (0.60) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL30741774 | 0.90 | CRBN (0.52) | CRBNESR1IKZF2WIZIKZF1 | |
| SCHEMBL27311012 | 0.90 | CRBN (0.53) | CRBNESR1IKZF2WIZIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574821-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |