⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792848 | 0.76 | KDM4C (0.34) | — | |
| SCHEMBL24921266 | 0.75 | CYP1A1 (0.52) | — | |
| SCHEMBL20970363 | 0.75 | MKNK1 (0.39) | — | |
| SCHEMBL20970328 | 0.75 | KDM4C (0.33) | — | |
| SCHEMBL21888512 | 0.75 | — | — | |
| SCHEMBL25669928 | 0.75 | — | — | |
| SCHEMBL5990507 | 0.74 | CLK1 (0.51) | — | |
| SCHEMBL22168092 | 0.73 | — | — | |
| SCHEMBL11190938 | 0.73 | — | — | |
| SCHEMBL24921474 | 0.73 | FGFR3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124471-A | Pyrazole ring explosive with high-energy and low-melting-point characteristics and synthesis method thereof | 中国工程物理研究院化工材料研究所 | 2022-09-30 | — | — | CN | claimed |
| CN-116874466-B | N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors | PFIZER INC. (US) | 2026-05-26 | — | — | CN | disclosed |
| CN-121974854-A | Synthesis method of fusion casting carrier explosive 4-methoxy-1-methyl-3, 5-dinitropyrazole | 西北工业大学 | 2026-05-05 | — | — | CN | disclosed |
| US-12312344-B2 | N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides useful as CCR6 inhibitors | PFIZER INC. (US) | 2025-05-27 | — | — | US | disclosed |
| US-20240368144-A1 | N-SUBSTITUTED-DIOXOCYCLOBUTENYLAMINO-3-HYDROXY-PICOLINAMIDES USEFUL AS CCR6 INHIBITORS | PFIZER INC. (US) | 2024-11-07 | — | — | US | disclosed |
| US-20240279215-A1 | NAMPT MODULATORS | CYTOKINETICS, INCORPORATED | 2024-08-22 | — | — | US | disclosed |
| CN-117794529-A | POLO-like kinase 4 inhibitors | 欧瑞克制药公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115124471-B | Pyrazole ring explosive with high energy and low melting point characteristics and synthesis method thereof | 中国工程物理研究院化工材料研究所 | 2024-02-13 | — | — | CN | disclosed |
| EP-3842433-B1 | PYRIDONE-PYRIMIDINE DERIVATIVE ACTING AS KRASG12C MUTEIN INHIBITOR | MEDSHINE DISCOVERY INC (CN) | 2023-11-01 | — | — | EP | disclosed |
| EP-3741756-B1 | PYRIDONE-PYRIMIDINE DERIVATIVE ACTING AS KRASG12C MUTEIN INHIBITOR | MEDSHINE DISCOVERY INC (CN) | 2023-11-01 | — | — | EP | disclosed |
| US-6288181-B1 | CATALYSIS WITH TRANSITION METAL METALLOCENE COMPOUND AND ETHER; REDUCING ELECTROSTATIC CHARGE | EASTMAN CHEMICAL COMPANY | 2001-09-11 | — | — | US | disclosed |
| US-6271321-B1 | CATALYTIC POLYMERIZATION OR COPOLYMERIZATION OF ETHYLENE AND OLEFIN MONOMERS | EASTMAN CHEMICAL COMPANY | 2001-08-07 | — | — | US | disclosed |
| WO-2000052068-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
| WO-2000052067-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
| US-4402727-A | Substituted azolylalkyl phenoxyphenoxyalkane-carboxylates as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-06 | — | — | US | disclosed |
| US-4382947-A | INSECTICIDES, MITICIDES, NEMATOCIDES, PARACITICIDES; VETERINARY MEDICINE; AGRICULTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-10 | — | — | US | disclosed |
| EP-0023326-B1 | N-METHYL-0-PYRAZOL(4)YL-CARBAMIC ACID ESTERS, PROCESS FOR THEIR SYNTHESIS AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1982-05-26 | — | — | EP | disclosed |
| US-4315008-A | Combating pests with O-ethyl-S-n-propyl-O-(1-substituted-pyrazol-4-yl)-(thiono)-thiolphosphoric acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | disclosed |
| EP-0012344-B1 | O-PYRAZOL-4-YL-O-ETHYL-S-N-PROPYL-(THIONO)THIOL-PHOSPHORIC-ACID ESTERS, PROCESS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1981-08-12 | — | — | EP | disclosed |
| EP-0023326-A1 | N-Methyl-0-pyrazol(4)yl-carbamic acid esters, process for their synthesis and their use as pesticides | BAYER AG (DE) | 1981-02-04 | — | — | EP | disclosed |