Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 17/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367078 | 0.82 | CRBN (0.66) | IKZF2CRBNIKZF1 | |
| SCHEMBL20046087 | 0.82 | CRBN (0.66) | IKZF2CRBNIKZF1 | |
| SCHEMBL21982392 | 0.82 | CRBN (0.66) | IKZF2CRBNIKZF1 | |
| SCHEMBL24319424 | 0.82 | CRBN (0.66) | IKZF2CRBNIKZF1 | |
| Hydrochloric Acid SCHEMBL29170744 | 0.81 | CRBN (0.52) | IKZF2CRBNIKZF1 | |
| Hydrochloric Acid SCHEMBL30121179 | 0.81 | CRBN (0.52) | IKZF2CRBNIKZF1 | |
| SCHEMBL24675866 | 0.81 | CRBN (0.42) | IKZF2CRBN | |
| Hydrochloric Acid SCHEMBL30635292 | 0.81 | CRBN (0.65) | IKZF2CRBNIKZF1 | |
| Hydrochloric Acid SCHEMBL20765337 | 0.81 | CRBN (0.65) | IKZF2CRBNIKZF1 | |
| Hydrochloric Acid SCHEMBL29158100 | 0.81 | CRBN (0.65) | IKZF2CRBNIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |