Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | HTR2B | P41595 | 4/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937272 | 1.00 | MCHR1 (0.40) | MCHR1SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL25937261 | 0.85 | MCHR1 (0.39) | MCHR1SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL25937273 | 0.85 | MCHR1 (0.39) | MCHR1SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL25937265 | 0.81 | HTR2A (0.33) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL25937270 | 0.77 | MCHR1 (0.36) | MCHR1SLC6A4HTR2CHTR2B | |
| SCHEMBL25937275 | 0.77 | MCHR1 (0.36) | MCHR1SLC6A4HTR2CHTR2B | |
| SCHEMBL25937331 | 0.74 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL25937333 | 0.73 | MCHR1 (0.49) | MCHR1SLC6A4SLC6A2SLC6A3CYP19A1 | |
| SCHEMBL25937256 | 0.72 | MCHR1 (0.39) | MCHR1CYP19A1 | |
| SCHEMBL25937253 | 0.72 | MCHR1 (0.36) | MCHR1HTR2CHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310423-A1 | CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2023-10-05 | — | — | US | disclosed |
| US-11707462-B2 | Checkpoint kinase 1 (CHK1) inhibitors and uses thereof | BOUNDLESS BIO, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230310423-A1 | CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | CHEK1, CHEK2, RAD1 | MCHR1 4279/4885SLC6A4 4862/4885SLC6A2 4844/4885 |
| US-11707462-B2 | Checkpoint kinase 1 (CHK1) inhibitors and uses thereof | CHEK1, CHEK2, RAD1 | MCHR1 4279/4885SLC6A4 4862/4885SLC6A2 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.