Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22049116 | 0.86 | AVPR1A (0.54) | AVPR1ATHRBHSD11B1HSD17B3GPBAR1 | |
| SCHEMBL2331511 | 0.83 | AVPR1A (0.55) | AVPR1ATHRBHSD11B1HSD17B3GPBAR1 | |
| SCHEMBL30673672 | 0.83 | AVPR1A (0.55) | AVPR1ATHRBHSD11B1HSD17B3GPBAR1 | |
| SCHEMBL30910105 | 0.82 | AVPR1A (0.51) | AVPR1ATHRBHSD11B1HSD17B3GPBAR1 | |
| SCHEMBL30673903 | 0.82 | AVPR1A (0.51) | AVPR1ATHRBHSD11B1HSD17B3GPBAR1 | |
| SCHEMBL26092817 | 0.82 | AVPR1A (0.51) | AVPR1ATHRBHSD11B1HSD17B3GPBAR1 | |
| SCHEMBL26093057 | 0.82 | AVPR1A (0.51) | AVPR1ATHRBHSD11B1HSD17B3GPBAR1 | |
| SCHEMBL29941296 | 0.81 | AVPR1A (0.56) | AVPR1ATHRBHSD11B1HSD17B3GPBAR1 | |
| SCHEMBL3663893 | 0.81 | AVPR1A (0.56) | AVPR1ATHRBHSD11B1HSD17B3GPBAR1 | |
| SCHEMBL3115822 | 0.80 | HSD17B3 (0.60) | AVPR1AHSD11B1HSD17B3GPBAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |