⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24147717 | 0.67 | — | — | |
| SCHEMBL25237741 | 0.60 | — | — | |
| SCHEMBL21779873 | 0.60 | — | — | |
| SCHEMBL6415574 | 0.59 | — | — | |
| SCHEMBL25492074 | 0.57 | MAPT (0.57) | — | |
| SCHEMBL14892540 | 0.55 | — | — | |
| SCHEMBL31519827 | 0.55 | — | — | |
| SCHEMBL23111396 | 0.55 | SLC22A2 (0.50) | — | |
| SCHEMBL24815136 | 0.55 | — | — | |
| SCHEMBL24625331 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270740-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. | 2024-08-15 | — | — | US | disclosed |
| WO-2023141852-A1 | CDK2 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 益方生物科技(上海)股份有限公司 | 2023-08-03 | — | — | WO | disclosed |