Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25938557 | 0.85 | KDM4E (0.52) | RECQLMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL25938648 | 0.85 | RECQL (0.60) | RECQLMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL25939236 | 0.85 | NPSR1 (0.46) | RECQLMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL25938715 | 0.83 | KMT2A (0.69) | RECQLMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL2883770 | 0.80 | RECQL (0.62) | RECQLMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL28776310 | 0.78 | RECQL (0.60) | RECQLMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL25938710 | 0.78 | RECQL (0.60) | RECQLMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL2885250 | 0.77 | MEN1 (0.74) | RECQLMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL25938616 | 0.77 | KDM4E (0.44) | MEN1KMT2AMAPTNPSR1GPR55 | |
| SCHEMBL2885256 | 0.76 | RECQL (0.52) | RECQLMEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |