Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9949471 | 0.89 | TSHR (0.55) | ALDH1A1MAPTTSHRL3MBTL1KMT2A | |
| SCHEMBL9949467 | 0.89 | TSHR (0.55) | ALDH1A1MAPTTSHRL3MBTL1KMT2A | |
| SCHEMBL26733025 | 0.83 | EPHX2 (0.41) | ALDH1A1MAPTTSHRLMNAKDM4E | |
| SCHEMBL25939640 | 0.82 | TP53 (0.55) | ALDH1A1GAAMAPTTSHRL3MBTL1 | |
| SCHEMBL3282634 | 0.82 | TP53 (0.55) | ALDH1A1GAAMAPTTSHRL3MBTL1 | |
| SCHEMBL25939514 | 0.82 | TP53 (0.55) | ALDH1A1GAAMAPTTSHRL3MBTL1 | |
| SCHEMBL27713735 | 0.80 | TSHR (0.50) | ALDH1A1MAPTTSHRL3MBTL1LMNA | |
| SCHEMBL31066651 | 0.80 | TSHR (0.50) | ALDH1A1MAPTTSHRL3MBTL1LMNA | |
| SCHEMBL10179066 | 0.80 | CYP1A2 (0.65) | ALDH1A1GAATSHRLMNAPOLB | |
| SCHEMBL9949804 | 0.80 | CYP1A2 (0.65) | ALDH1A1GAATSHRLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141852-A1 | CDK2 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 益方生物科技(上海)股份有限公司 | 2023-08-03 | — | — | WO | disclosed |