Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292200 | 0.96 | PPARA (0.55) | PPARAPPARGGAANPSR1KDM4E | |
| Hydrochloric Acid SCHEMBL28797126 | 0.91 | GAA (0.55) | PPARAPPARGGAANPSR1KDM4E | |
| SCHEMBL9651741 | 0.88 | PPARA (0.67) | PPARAPPARGGAANPSR1ALDH1A1 | |
| SCHEMBL8554090 | 0.86 | GAA (0.59) | PPARAPPARGGAANPSR1KDM4E | |
| Hydrochloric Acid SCHEMBL6981890 | 0.85 | GAA (0.57) | PPARAPPARGGAANPSR1KDM4E | |
| SCHEMBL12869146 | 0.85 | PPARA (0.69) | PPARAPPARGGAANPSR1PLA2G4A | |
| SCHEMBL28405319 | 0.83 | PPARA (0.71) | PPARAPPARGGAANPSR1ALDH1A1 | |
| SCHEMBL15922116 | 0.83 | PPARA (0.71) | PPARAPPARGGAANPSR1ALDH1A1 | |
| SCHEMBL11817150 | 0.83 | PPARA (0.63) | PPARAPPARGGAANPSR1KDM4E | |
| SCHEMBL9267668 | 0.83 | GAA (0.70) | GAANPSR1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146892-A1 | BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |