Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21703067 | 0.86 | MAP4K1 (0.56) | MAP4K1 | |
| SCHEMBL25944837 | 0.79 | MAP4K1 (0.63) | MAP4K1 | |
| SCHEMBL25945205 | 0.79 | MAP4K1 (0.63) | MAP4K1 | |
| SCHEMBL21703386 | 0.78 | MAP4K1 (0.53) | MAP4K1 | |
| SCHEMBL21703381 | 0.77 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL30203357 | 0.77 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL23452762 | 0.75 | MAP4K1 (0.46) | MAP4K1 | |
| SCHEMBL21685079 | 0.73 | MAP4K1 (0.48) | MAP4K1 | |
| SCHEMBL21685476 | 0.72 | MAP4K1 (0.58) | MAP4K1 | |
| SCHEMBL25945832 | 0.72 | MAP4K1 (0.62) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |