Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25946340 | 0.91 | — | — | |
| SCHEMBL27059057 | 0.83 | KCNH2 (0.36) | KCNH2TACR1CYP11B1CYP11B2 | |
| SCHEMBL16446934 | 0.74 | HRH3 (0.39) | KCNH2TACR1CYP11B1CYP11B2 | |
| SCHEMBL27059055 | 0.73 | OPRL1 (0.31) | — | |
| SCHEMBL16659515 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL21285292 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL25946342 | 0.71 | — | — | |
| SCHEMBL25946339 | 0.71 | — | — | |
| SCHEMBL7986537 | 0.70 | KMT2A (0.40) | KCNH2CYP11B1CYP11B2 | |
| SCHEMBL25946338 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223750-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND WHICH CONTAINS PYRIMIDINE | Asahi Kasei Pharma Corporation (JP) | 2023-08-09 | — | — | EP | disclosed |