Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25947075 | 0.97 | TSHR (0.50) | TSHRMAPTP4HBKMT2AHTT | |
| SCHEMBL25947605 | 0.87 | TSHR (0.47) | TSHRMAPTP4HBKMT2AHTT | |
| SCHEMBL25947897 | 0.84 | RAD52 (0.45) | TSHRMAPTP4HBKMT2AHTT | |
| SCHEMBL25947609 | 0.84 | TSHR (0.36) | TSHRMAPTP4HBKMT2AHTT | |
| SCHEMBL25947606 | 0.83 | TSHR (0.55) | TSHRMAPTP4HBKMT2AHTT | |
| SCHEMBL25947208 | 0.82 | RAD52 (0.47) | TSHRMAPTP4HBKMT2AHTT | |
| SCHEMBL25946923 | 0.82 | RAD52 (0.47) | TSHRMAPTP4HBKMT2AHTT | |
| SCHEMBL25947110 | 0.80 | RAD52 (0.49) | TSHRMAPTP4HBKMT2AHTT | |
| SCHEMBL25946422 | 0.80 | RAD52 (0.49) | TSHRMAPTP4HBKMT2AHTT | |
| SCHEMBL25947070 | 0.80 | TSHR (0.58) | TSHRMAPTP4HBKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |