Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 17/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21703333 | 0.88 | MAP4K1 (0.43) | MAP4K1MAPK14 | |
| SCHEMBL25942399 | 0.86 | MAP4K1 (0.44) | MAP4K1MAPK14PTGER3 | |
| SCHEMBL21684478 | 0.78 | MAP4K1 (0.83) | MAP4K1 | |
| SCHEMBL21684482 | 0.78 | MAP4K1 (0.83) | MAP4K1 | |
| SCHEMBL21684481 | 0.78 | MAP4K1 (0.83) | MAP4K1 | |
| SCHEMBL25942449 | 0.78 | MAP4K1 (0.45) | MAP4K1MAPK14 | |
| SCHEMBL31450201 | 0.78 | MAP4K1 (0.67) | MAP4K1 | |
| SCHEMBL25948635 | 0.76 | MAP4K1 (0.46) | MAP4K1MAPK14PTGER3 | |
| SCHEMBL25948643 | 0.76 | MAP4K1 (0.46) | MAP4K1MAPK14PTGER3 | |
| SCHEMBL21703332 | 0.74 | MAP4K1 (0.55) | MAP4K1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |