Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 12/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21685309 | 0.89 | MAP4K1 (0.45) | MAP4K1RECQLELANEP2RX3PIN1 | |
| SCHEMBL21684901 | 0.80 | MAP4K1 (0.57) | MAP4K1RECQLELANEP2RX3ALDH1A1 | |
| SCHEMBL21684339 | 0.77 | MAP4K1 (0.50) | MAP4K1RECQLELANEHTT | |
| SCHEMBL21685878 | 0.76 | MAP4K1 (0.47) | MAP4K1 | |
| SCHEMBL21685939 | 0.73 | MAP4K1 (0.43) | MAP4K1RECQLELANEP2RX3ALDH1A1 | |
| SCHEMBL31304001 | 0.72 | MAP4K1 (0.44) | MAP4K1RECQLELANEP2RX3ALDH1A1 | |
| SCHEMBL21684342 | 0.72 | ELANE (0.40) | MAP4K1RECQLELANEP2RX3ALDH1A1 | |
| SCHEMBL21684437 | 0.72 | MAP4K1 (0.44) | MAP4K1RECQLELANEP2RX3ALDH1A1 | |
| SCHEMBL21684452 | 0.71 | MAP4K1 (0.43) | MAP4K1RECQLELANEP2RX3ALDH1A1 | |
| SCHEMBL21685778 | 0.71 | MAP4K1 (0.42) | MAP4K1RECQLELANEALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |