Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799529 | 0.85 | HPGD (0.44) | NR1H2USP2SMN1; SMN2SETD7CHRM2 | |
| SCHEMBL2797597 | 0.85 | HPGD (0.44) | NR1H2USP2SMN1; SMN2SETD7CHRM2 | |
| SCHEMBL2797599 | 0.85 | HPGD (0.44) | NR1H2USP2SMN1; SMN2SETD7CHRM2 | |
| SCHEMBL20898517 | 0.84 | USP2 (0.46) | NR1H2EPHX2USP2SMN1; SMN2SETD7 | |
| SCHEMBL20905401 | 0.84 | USP2 (0.46) | NR1H2EPHX2USP2SMN1; SMN2SETD7 | |
| SCHEMBL20905408 | 0.84 | USP2 (0.46) | NR1H2EPHX2USP2SMN1; SMN2SETD7 | |
| SCHEMBL16117984 | 0.84 | USP2 (0.40) | NR1H2EPHX2USP2SMN1; SMN2SETD7 | |
| SCHEMBL15346272 | 0.83 | NR1H2 (0.40) | NR1H2USP2SMN1; SMN2SETD7CHRM2 | |
| SCHEMBL15346270 | 0.83 | NR1H2 (0.40) | NR1H2USP2SMN1; SMN2SETD7CHRM2 | |
| SCHEMBL16094196 | 0.81 | SETD7 (0.38) | NR1H2USP2SMN1; SMN2SETD7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223750-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND WHICH CONTAINS PYRIMIDINE | Asahi Kasei Pharma Corporation (JP) | 2023-08-09 | — | — | EP | disclosed |